“We bring clinically-inspired skincare that addresses real-life concerns to our customers. Using my 20+ years of expertise and medical observations, we develop products using innovative formulas that are engineered using the most sophisticated methods for efficient penetration of the skin and the highest levels of efficacy. We strive to bring the best of Harley Street to your home, creating skincare that can replicate in-clinic treatments, all while feeling opulently indulgent and a sensorial pleasure.”
Dr. Yannis Alexandrides MD Founder of 111SKIN and renowned Cosmetic Surgeon.

Harley Street


111SKIN is the culmination of twenty years of surgical knowledge, high-tech ingredients, and cutting-edge innovation; founded by globally renowned Harley Street cosmetic surgeon Dr. Yannis Alexandrides, the original formula was developed to help his patients’ skin heal after trauma and given complimentary after treatments for more effective results and improved healing time.


Collaborating with space scientists who researched the acceleration of ageing in astronauts, Dr. Yannis wanted to produce a product which could induce skin’s own reparative processes to alleviate scarring and inflammation, and protect against environmental pollutants. The formula included NAC Y2, a trio of actives with superior antioxidant capabilities, one of which stimulates the production of Glutathione – the body’s most powerful intracellular antioxidant. After noticing their skin looking younger and feeling smoother, patients started requesting more of the serum and soon demand outstripped supply.


Believing in prevention, rather than intervention, as means of maintaining skin health and vitality he realised that many people could benefit from this formula, and worked together with his wife Eva to create the 111SKIN brand, evolving from one single product to five ranges. Taking inspiration from his 111 Harley St. clinic, each product is carefully researched and formulated to address specific skincare concerns that he sees on a daily basis such a premature ageing, oily or spot-prone skin, lacklustre complexions, hyperpigmentation, and dehydration. There are also targeted products that are focused on damage-prone areas such as the neck and décolletage, under eyes, and lips.


111SKIN is committed to delivering skincare which is science-led, pioneering, medically-inspired, and able to provide results that are comparable to in-clinic procedures.